More and more people now do extensive genetic screening, including whole-genome sequencing. Are there particular gene panels that can alert the person that they might be predisposed to NASH, Even though they might not have metabolic syndrome, they might not be overweight? Yeah, so, in fact, even 23andme and commercial DNA testing platforms will indicate to patients that they might be at heightened risk for NASH. So we don't use genetics for screening. It's not appropriate because there are probably many patients who have the genetic risk but don't have the NAFLD or NASH. On the other hand, once we diagnose NAFLD or NASH, the presence of genetic risks may tell us that that patient is at heightened risk for progression and may require more assertive, or more careful monitoring, or more frequent monitoring.
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