Patients ask important questions. Certainly, they should ask questions about how to improve their liver health. And that includes should they or can they drink any alcohol? And certainly, if they're obese or overweight and they have fat in the liver. We need to work with them and nutritional expertise. Because the first mainstay of therapy for NASH, which I really haven't mentioned but should have, is weight loss, weight loss, and exercise. And in fact, if you look at all the benefits of weight loss, it probably has broader benefits on NASH than any single drug we've identified yet. And so we have to be very assiduous and consistent in our message that for NASH patients who have elevated weight, we really need to work hard with them over the long run to reduce their weight. It's very hard. That's why there are all these NASH drugs being developed. Dr. Scott Friedman, MD.: But only 5% of patients who lose weight can keep it off to the extent that it will benefit their NASH. Dr. Scott Friedman, MD.: But there's no question that for patients with NASH, significant weight loss, meaning 10 kilograms or more, can really have a profound impact on improving their liver health.
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