Better synthetic Curosurf medication to save lungs of babies. 5

Better synthetic Curosurf medication to save lungs of babies. 5

Better synthetic Curosurf medication to save lungs of babies. 5

Can we help?

This site is protected by hCaptcha and the hCaptcha Privacy Policy and Terms of Service apply.

Dr. Anton Titov, MD. You have dedicated your life to treating and helping premature babies who would otherwise die if it were not for the medication that you co-developed. But you still are very active in research now and you are developing a synthetic medication. Can you tell us a little bit more about the synthetic medication that you are developing that supposedly will be much easier to scale up? Dr. Anton Titov, MD. Because you don't have to take in animal material anymore. Because, of course, if we have one pig, they were not big. It can produce two or three vials of surfactant. At least you can treat 2 3 babies, not more than that. You need huge amount of pigs. Dr. Anton Titov, MD. You can't scale up too much. Dr. Anton Titov, MD. You can't treat grown ups with lung diseases. Already in the late 90s, we knew the exact composition of surfactant. Phospholipid composition. The sequence of the peptides. Dr. Tore Curstedt. We thought that in the end of the 90s, beginning 2000, we will have a synthetic surfactant. But we had problem because we tried to make recombinant peptides. The proteins, SPB and SPC, it was no problem to get the right sequence. But SPC, for example, is an alpha helix. But it was not an alpha helix, when we made a recombinant SPC. Medical second opinion is important. Dr. Anton Titov, MD. Dr. Tore Curstedt. That was the problem. The structure, three-dimensional structure. Then we had to start making analogs. Have made many different analogs during the last 20 years. Now, we have two very good analogs. Dr. Tore Curstedt. We have combined these analogs with phospholipids and we have tested it in our rabbit models. Also safely studied in three countries, in Czech Republic. In Germany and England. It functions very well. Clinical trial has started a couple of months ago, an it will start in Europe.

More from Public Health
You must get treatment for hypertension and atherosclerosis. How to improve your health? 17
¥0
Salt intake in hypertension and heart failure. Reduce salt? Increase potassium? 16
¥0
Potassium and blood pressure connection. Can dietary potassium be dangerous? 2
¥0
Immunotherapy in breast cancer. Immunotherapy is not a magic treatment. 11
¥0
Most patients with fatty liver disease & NASH do not have symptoms. Alcohol is often not to blame. 17
¥0
How to improve health of your liver? Difficulty to keep low weight. 16
¥0
Recently viewed Expert Conversations

Get your treatment plan refined to perfection by a panel of 3 to 10+ top doctors who are perfect for you.

Get your treatment plan refined to perfection by a panel of 3 to 10+ top doctors who are perfect for you.

Get your treatment plan refined to perfection by a panel of 3 to 10+ top doctors who are perfect for you.


Can we help?

We can find perfect surgeons or medical specialists to perform your treatment.

We can find perfect surgeons or medical specialists to perform your treatment.


How it works
We can find perfect surgeons or medical specialists to perform your treatment.